Breaking down cancer's defense for future vaccines
Researchers at the EPFL have identified an important mechanism that could lead to the design of more effective cancer vaccines. Their discovery of a new-found role of the lymphatic system in tumour...
View ArticleGenetically modified mice to visualize in vivo inflammation and metastasis
One of the major routes of tumor cell dissemination to form metastasis at distant organs in the body is the lymphatic system. To study this process, still poorly understood, and to gain information on...
View ArticlePutting pressure on lymphoedema
(Medical Xpress) -- Researchers from Flinders University are trialling a new treatment for lymphoedema of the legs, giving fresh hope to sufferers of the disabling condition.
View ArticleBoost your immune system with a healthy lifestyle
Your immune system is your defense against disease. Its many different parts need to work in balance and harmony to protect our bodies from harmful germs and viruses; in essence to attack and destroy...
View ArticleObesity may raise odds for painful leg condition
(HealthDay) -- The health risks associated with being overweight and obese are well publicized, but new research may add another condition to this list: leg lymphedema, pain and swelling due to...
View ArticleBlood test could lead to improved diagnosis and treatment of breast cancer
Scientists have discovered that a simple blood test could lead to better diagnosis and treatment for early-stage breast cancer patients, according to an Article published Online First in The Lancet...
View ArticleLaser-light testing of breast tumor fiber patterns helps show whose cancer is...
Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of...
View ArticleNew insight into RASopathy-associated lymphatic defects
The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
View ArticleLymphatic vasculature: A cholesterol removal system
Reverse cholesterol transport is a process in which accumulated cholesterol is removed from tissues, including the artery wall, and transported back to the liver for excretion. Little is known about...
View ArticleTranscription factors regulating blood oxygen linked to melanoma metastases
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
View ArticleGenetic markers linked to the development of lymphedema in breast cancer...
A new UCSF study has found a clear association between certain genes and the development of lymphedema, a painful and chronic condition that often occurs after breast cancer surgery and some other...
View ArticlePhotoacoustics spares healthy lymph nodes in patients with metastasized cancer
If a tumour has spread through the lymph nodes, the decision is often taken to exercise caution and remove extra tissue, to prevent it from spreading further. This often involves the removal of healthy...
View ArticleLymphatic fluid takes detour
When tumours metastasise, they can block lymphatic vessels, as researchers from ETH Zurich have discovered using a new method. The lymphatic fluid subsequently has to find a new path through the...
View ArticleStudy supports role for skin sodium in blood pressure regulation
It's time to expand the models for blood pressure regulation, according to clinical pharmacologist Jens Titze, M.D. Titze and his colleagues have identified a new cast of cells and molecules that...
View ArticleBrain's 'garbage truck' may hold key to treating Alzheimer's and other disorders
In a perspective piece appearing today in the journal Science, researchers at University of Rochester Medical Center (URMC) point to a newly discovered system by which the brain removes waste as a...
View ArticleTo sleep, perchance to clean: Study reveals brain 'takes out the trash' while...
In findings that give fresh meaning to the old adage that a good night's sleep clears the mind, a new study shows that a recently discovered system that flushes waste from the brain is primarily active...
View ArticleAnti-cancer lymphatic drugs show potential
Researchers at the University of Auckland are using zebrafish embryos to investigate potential medicines that will inhibit the spread of some cancers via the lymphatic system.
View ArticleNew treatment resolves a hazardous airway complication in child with heart...
A case study published recently in the journal Pediatrics describes an innovative, minimally invasive procedure that treated plastic bronchitis, a potentially life-threatening disease, in a...
View ArticleOrigins of left-sided gut artery, lymphatic system discovered
Researchers have understood very little about how blood and lymphatic vessels form in the mammalian gut – until now.
View ArticleThe origin of the lymphatic vasculature uncovered
In a new study, published in Cell Reports, researchers at Uppsala University describe a novel mechanism by which lymphatic vessels form during embryonic development. The finding may open new...
View ArticleHow cancer tricks the lymphatic system into spreading tumors
Swollen lymph nodes are often the earliest sign of metastatic spread of cancer cells. Now cancer researchers and immunologists at Sweden's Karolinska Institutet have discovered how cancer cells can...
View ArticleLymphatic cells grown in the lab for the first time
For over one hundred years, scientists have debated the question of the origins of the lymphatic system - a parallel system to the blood vessels that serves as a conduit for everything from immune...
View ArticleMissing link found between brain, immune system
In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune...
View ArticleStudy: Statins may stem tumor growth
(Medical Xpress)—One of the world's top selling drugs potentially also acts against the growth of new lymphatic vessels, with potential implications for cancer therapy. This surprising finding was...
View ArticleNew study confirms immune cells are guided by gradients
(Medical Xpress)—A group of researchers in Austria and Switzerland has for the first time proven that immune cells migrate along chemical concentration gradients. This process has long been assumed but...
View ArticleNew function for a messenger molecule
ETH Zurich Assistant Professor Cornelia Halin and her colleagues have discovered a new function of the well-known messenger protein interleukin-7: it facilitates the drainage of lymph fluid from...
View ArticleResearchers describe regulatory protein controlling the patterning of the...
The lymphatic vasculature is vital for the function of the immune system, but its development is poorly understood in comparison to that of the blood vasculature from which it arises. The vessels that...
View ArticleFlow means 'go' for proper lymph system development
The lymphatic system provides a slow flow of fluid from our organs and tissues into the bloodstream. It returns fluid and proteins that leak from blood vessels, provides passage for immune and...
View ArticleAn invisible system to rescue the heart
Heart failure affects over one million people in France. Although the blood system is the first to have been explored for the purpose of improving heart function, a study by Inserm has revealed the...
View ArticleBlocking the migration of cancer cells to destroy them
Lymphoma is a cancer that affects lymphocytes, a type of white blood cell. The disease originates in a lymphoid organ (lymph node, spleen, or bone marrow) before spreading through the blood to...
View Article
More Pages to Explore .....